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In 2017, Domain Therapeutics and Pfizer signed a collaboration agreement to accelerate the validation of novel GPCR drug targets using bioSens-All™ (see press release)


Program description

Multi-target collaboration for rare diseases

  • Discovery
  • Candidate
  • Preclinical
  • Clinical

The multi-target drug discovery program aims at validating potential targets across a range of therapeutic indications by probing the structure-function relationships of various amino acid substitutions in each GPCRs.

The collaboration is based on our proprietary platform bioSens-All™ which enables to assess the impact of mutations on different signaling pathways engaged by GPCRs.


Other programs

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Precision Medicine and Immunotherapy of Sarcoma

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CXCR4 biased agonist

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