Join our free webinar : The discovery and challenges of antibodies targeting GPCRs on april 20, 2021 at 03 pm CEST
Join us live for our upcoming webinar, in collaboration with Drug Target Review. Our Chief Technology Officer, Xavier Leroy and Martine Smit, Professor of Target and Systems Biochemistryat the University of Amsterdam, will discuss the progress achieved in G protein-coupled receptor (GPCR) therapeutic antibody-based discovery and development.
GPCRs play a key role in cell physiology and homeostasis and are implicated in various diseases including cancer, immune-mediated and inflammatory disorders, cardiovascular, as well as neurological and metabolic diseases. While GPCRs have traditionally been regarded as the domain for small-molecule drugs, these only target a very small proportion of receptors. Technical developments that are widely applied to antibody discovery have further empowered GPCR-monoclonal antibody (mAb) and nanobody discovery.